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Pass box is one of the cleanroom systems, which is used to transfer materials from one side to other side through controlled environment in order to avoid airborne cross contamination. As the name states itself, the primary and only work of a pass box is to pass material from one side to other without raising contamination concern and if any particulate matter presents on the material surface, it swipes away during the operation. Interlocking door mechanism is the prime feature of a pass box, when door at one side is open the door at other side remains closed. It is popular with other names such as cleanroom pass through, clean transfer window and transfer hatch; in addition, it is widely used in microbiology laboratories in food, pharmaceutical and chemical industries.